AOD-9604
Also known as Anti-Obesity Drug 9604, hGH Fragment 176-191
AOD-9604 is a modified fragment of human growth hormone (amino acids 176–191). Unlike HGH itself, it has no anabolic or diabetogenic effects — it targets fat burning specifically by mimicking the way HGH regulates fat metabolism.
How it works
Binds a beta-adrenergic receptor independently of the GH receptor. Activates fat cell lipolysis and inhibits fatty acid uptake. Has no IGF-1 stimulation — purely lipolytic.
Benefits
- Direct fat burning — stimulates lipolysis
- Inhibits lipogenesis (fat cell creation)
- No effect on blood sugar or insulin
- No anabolic effects (no muscle growth or organ effects)
- Joint and cartilage benefits (surprising secondary finding)
- Very safe profile compared to HGH
Dosing
300–500 mcg · Once daily (fasted — 30 min before food)
Must be injected fasted for best effect. Some protocols use 300mcg SubQ in the abdominal area.
Ranges reflect commonly cited research protocols, not a prescription. Dose with a licensed provider.
Reconstitution
5mg vial with 2mL BAC water = 2.5mg/mL
Helix’s free reconstitution calculator gives you the exact draw volume → get the app
Common stacks
Reported side effects
- Very well tolerated
- Occasional redness at injection site
- No systemic side effects typical
Who it’s for
Those specifically targeting fat loss without other anabolic effects. Good for those sensitive to HGH side effects who still want its fat-burning properties.
Track AOD-9604 in Helix
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