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CJC-1295 No DAC + Ipamorelin Blend

Also known as CJC/Ipa blend, Mod GRF + Ipamorelin, GH peptide blend, CJC Ipamorelin combo

The most popular growth hormone secretagogue blend — combining a GHRH analogue (CJC-1295 No DAC / Mod GRF 1-29) with a selective GHRP (Ipamorelin). These work synergistically: CJC-1295 amplifies the GH pulse while Ipamorelin triggers the release. The result is a strong, clean GH pulse that mimics natural pulsatile release without the cortisol, prolactin, or hunger side effects of older GHRPs.

Typical dosing
100–200 mcg · Once to twice daily
Administration
SubQ
Half-life
CJC-1295 No DAC: 30 min; Ipamorelin: ~2 hours
Level
intermediate

How it works

CJC-1295 No DAC binds GHRH receptors on somatotrophs, amplifying GH pulse amplitude. Ipamorelin binds ghrelin/GHS receptors, triggering GH release. Combined, they produce a synergistic GH pulse 2–10x larger than either alone while maintaining a clean hormonal profile.

Benefits

  • Strong GH pulse — synergistic GHRH + GHRP combination
  • Clean profile — no cortisol or prolactin increase (unlike GHRP-2/6)
  • Improved body composition — fat loss and lean mass gains
  • Deep sleep enhancement and recovery
  • Anti-aging via IGF-1 elevation
  • Improved skin, hair, and joint health
  • Enhanced recovery from training

Dosing

100–200 mcg · Once to twice daily

Each component: 100–200mcg per dose. Pre-blended 6mg/6mg vial. Must inject when fasted (1h before or 2h after eating) for best GH response. Bedtime dosing ideal.

Ranges reflect commonly cited research protocols, not a prescription. Dose with a licensed provider.

Reconstitution

12mg total blend with 2mL BAC water = 6mg/mL (3000mcg/mL each component). 100mcg dose = ~0.033mL.

Helix’s free reconstitution calculator gives you the exact draw volume → get the app

Common stacks

Ibutamoren (MK-677)BPC-157IGF-1 LR3

Reported side effects

  • Mild water retention initially
  • Tingling/numbness (carpal tunnel-like, rare)
  • Headaches
  • Injection site redness

Who it’s for

Adults seeking GH optimization without pharmaceutical HGH. Intermediate users in anti-aging or body composition protocols. Those who want clean GH support without appetite stimulation.

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