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Thymagen

Also known as Glu-Asp-Gly, thymic tripeptide bioregulator

Thymagen is a tripeptide (Glu-Asp-Gly) thymic bioregulator from Khavinson's series. It targets thymic epithelial cells to restore T-cell differentiation and normalize immune function. Distinct from Thymulin (FTS) and Thymalin, it is a shorter synthetic peptide designed to mimic the organ-specific bioregulatory signal of the thymus. Particularly useful for immune aging and immunosenescence.

Typical dosing
100–500 mcg · Once daily
Administration
SubQ, IM
Half-life
Short; minutes to hours
Level
intermediate

How it works

Tripeptide that penetrates thymic epithelial cell nuclei and interacts with chromatin, normalizing gene expression in thymus tissue. Stimulates production of thymic hormones and promotes T-cell precursor differentiation into mature T-cells. Similar mechanism to Thymosin Alpha-1 but via epigenetic regulation.

Benefits

  • Restores thymic epithelial cell function
  • Improves T-cell differentiation and maturation
  • Enhances immune response to infections
  • Reduces immunosenescence (immune aging)
  • Supports immune recovery after illness or stress
  • May reduce autoimmune dysregulation

Dosing

100–500 mcg · Once daily

Course: 100–500mcg/day SubQ for 10–30 days. Can be combined with Thymalin or Thymosin Alpha-1 for enhanced immune effect.

Ranges reflect commonly cited research protocols, not a prescription. Dose with a licensed provider.

Reconstitution

25mg vial with 2–5mL BAC water. Refrigerate.

Helix’s free reconstitution calculator gives you the exact draw volume → get the app

Common stacks

Reported side effects

  • Generally well tolerated
  • Mild injection site irritation
  • Theoretical autoimmune flare in susceptible individuals

Who it’s for

Adults with compromised immunity, frequent infections, or significant immune aging. Those recovering from illness, chemotherapy, or immunosuppressive therapy.

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