HCG (Human Chorionic Gonadotropin)
Also known as Human Chorionic Gonadotropin, hCG, Pregnyl, Novarel
A glycoprotein hormone that mimics luteinizing hormone (LH), signaling the testes to produce testosterone and maintain their size and fertility. A staple of men's-health and TRT clinics, used alongside testosterone to preserve natural production.
How it works
Binds LH receptors on testicular Leydig cells, stimulating testosterone and intratesticular steroidogenesis. In women it supports ovulation and the corpus luteum.
Benefits
- Maintains testicular size and function on TRT
- Supports fertility and sperm production
- Restores endogenous testosterone
- Can aid post-cycle recovery
Dosing
250–1000 IU · 2-3x per week
Common TRT-adjunct dosing is 250-500 IU 2-3x/week SubQ. Fertility protocols may use more. Excessive doses cause estrogen rise and desensitization.
Ranges reflect commonly cited research protocols, not a prescription. Dose with a licensed provider.
Reconstitution
Lyophilized powder reconstituted with BAC water; refrigerate and use within ~30-60 days.
Helix’s free reconstitution calculator gives you the exact draw volume → get the app
Common stacks
Reported side effects
- Estrogen elevation / gynecomastia
- Acne
- Mood changes
- Water retention
- Testicular discomfort
- Desensitization at high doses
Who it’s for
Men on TRT who want to preserve fertility and testicular function, or those in a restart/PCT protocol. Best under clinic supervision.
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